Great Article on CBD – Did you learn anything about how the efficacy of the CBC is affected by the source species? e.g. Cannabis vs Hemp. Also, Sativa vs. Indica. All of the referenced studies just state CBC, do you know what is the typical source of CBD used in these type of studies? CBC oil from Hemp is readily and cheaply available on the internet from many companies, however I have read that the efficacy of Hemp derived CBD is less than from Cannabis. Any thoughts? Thanks!
In the United States, cannabidiol is a Schedule I drug under the Controlled Substances Act.[60] This means that production, distribution, and possession of CBD is illegal under federal law. In addition, in 2016 the Drug Enforcement Administration added "marijuana extracts" to the list of Schedule I drugs, which it defined as "an extract containing one or more cannabinoids that has been derived from any plant of the genus Cannabis, other than the separated resin (whether crude or purified) obtained from the plant."[61] Previously, CBD had simply been considered "marijuana", which is a Schedule I drug.[60][62]

Enter CBD oil: an anti-inflammatory and anti-anxiety compound. I have seen in my own life, and many of my patients' lives, the positive impact CBD oil can have on anxiety. Studies have found that CBD oil is a natural anxiolytic (anxiety calmer) and is effective in treating social anxiety. CBD calms anxiety naturally without the potential side effects of pharmaceutical anti-anxiety medications.

There were distinct changes in neural activation associated with the significant anxiolytic effects provided by CBD.  When compared to the placebo, administration of CBD significantly: increased ECD tracer uptake in the right posterior cingulate gyrus and decreased ECD tracer uptake in the left parahippocampal gyrus, hippocampus, and inferior temporal gyrus.  Researchers concluded that reductions in social anxiety from CBD are related to modulation of neural activity in the limbic and paralimbic regions.
Further testing found what the world now knows: This compound is the plant’s principal active ingredient, its mind-altering essence—the stuff that makes you high. Mechoulam, along with a colleague, had discovered tetrahydrocannabinol (THC). He and his team also elucidated the chemical structure of cannabidiol (CBD), another key ingredient in marijuana, one that has many potential medical uses but no psychoactive effect on humans.
CBD oil extracted from hemp — no matter how it’s consumed — works with the body’s ECS system to replenish cannabinoids and regulate homeostasis. The substance is also anti-anxiolytic, meaning it reduces feelings of anxiety — a common source of sleep problems in adults. For these reasons, hemp-based CBD oil can be highly beneficial for people with insomnia whether they struggle with sleep onset (falling asleep) or sleep maintenance (staying asleep). In addition to insomnia, CBD oil may lead to improvements for the following sleep disorders:
One of the most common ways that people consume CBD is through a tincture. Tinctures are placed under the tongue, held for a brief period, and then swallowed. Tinctures are easy to take, easy to store, and can come in different flavors, making them tasty to consume. There are many different tinctures on the market coming in different sizes and concentrations. They vary in how the CBD is grown, extracted, and tested. Let’s take a further look.
CBD is showing real promise as a compound that can contribute to protecting the brain, thanks to its anti-oxidant and anti-inflammatory abilities. Scientists are investigating its role in neurogenesis and its ability to help the brain heal from injury, and as a treatment for neurodegenerative disease. Research suggests that CBD may help to reduce brain damage from stroke or other neurological injury. And CBD is increasingly looked to as a possible therapy for several neurodegenerative diseases, including Parkinson’s, Alzheimer’s, and multiple sclerosis.
Stephanie Kahn, who with her husband, Jeffrey, runs the Takoma Wellness Center, a medical marijuana dispensary in Northwest Washington, says that about half of her 1,200 patients use CBD-rich products. Her dispensary offers several strains of high-CBD cannabis as well as CBD oil, with different ratios of CBD and THC, each of which she recommends for particular conditions. “We get questions about it every day,” she says. “A lot of our patients get relief with this, and a lot of times this works better than pharmaceutical drugs.”
Cost: For high quality, unadulterated CBD – you’re going to pay a hefty price. Assuming you don’t want a product with pesticides, herbicides, fertilizers, and/or other chemical additives, you’ll likely end up paying a significant amount for just a few doses.  Until scientists figure out a way to enhance CBD’s bioavailability, regular users of oral CBD may feel as if the supplement is too costly.  Fortunately, there are other ways to administer cannabidiol such as vaporizing the oil – which will likely save consumers money.
Kent, My mother has suffered from severe migraines since she was a child. Six weeks ago, she received the hemp oil tincture (I do not know what dosage). She does not take it daily. She rubs a drop or two on her temples at the start of a migraine. The drops worked more effectively for her than her medication did, and now that is all she uses. Hope this helps.
In recent years, CBD has generated a tremendous amount of interest among consumers, clinicians, and scientists. Why? Not only does evidence suggest CBD counteracts many of THC’s adverse effects, but numerous animal studies and accumulating evidence from human experimental, clinical, and epidemiological studies suggest CBD has powerful anti-anxiety properties. Administered acutely (“as needed”), it appears safe, well-tolerated, and may be beneficial to treat a number of anxiety-related disorders, including:
Despite these limitations, this is the first controlled study to evaluate the effects of CBD on sleep architecture using polysomnography. Although the absence of interference with the sleep cycle is not sufficient for concluding that sleep is not affected, the results obtained contribute for the understanding of the effects of CBD in the modulation of sleep in humans.
What did I experience? As was the case for Talansky, my sleep improved almost immediately. It wasn’t that I slept more; I felt like I slept better—more soundly, less waking during the night, more often getting out of bed feeling refreshed. By the second week I noticed less overall creakiness while going about daily activities; CBD advocates would say the products had lowered systemic inflammation. Those two changes made me feel like I was recovering better from training, which led to being more eager to train, and feeling better while doing so.

Yet when one looks at the industry more broadly, there is cause for concern. In February, as part of an investigation into the marketing claims of six hemp oil companies, the FDA analyzed 18 CBD products. What it found was disturbing: Many of these supposed CBD products were entirely lacking in CBD. Of the products tested, six contained no cannabinoids whatsoever. Another 11 contained less than 1 percent CBD. The product that tested highest in CBD, at 2.6 percent, was a capsule for dogs. In states that have legalized CBD, regulations can require CBD products to contain at least 5 percent CBD, more often 10 or 15 percent.
There's plenty of anecdotal evidence that CBD helps treat a variety of ailments. People are turning to oils, gummies, and other CBD food and drink products to relax at the end of a long day. Retired NFL players are using CBD to manage physical pain, debilitating headaches, and sleeplessness. Spa clients are even using CBD skin products to fight signs of aging.
I am currently going through red skin syndrome/topical steroid withdrawal. The only cure as of now is time(6 months to 3 years) and waiting out horrible eczema-like flares. My main issue is burning/tingling skin that is almost constant. Steroids close off blood vessels and when you stop them they 'wake' up causing this nerve discomfort/pain. I've been smoking medical cannabis for the duration of my recovery(1.5 years) and It's done wonders except that the flare is around my mouth and I'm afraid the smoking is causing more issues.. as well as helping. I need to step up my game and take a different approach. I am wondering how to go about using cbd but I don't know where to start and was wondering if you could help. Thank you
Doesn’t affect cognition: A major drawback associated with anxiolytics is that many affect cognitive function. Sure it helps to take a pill and have less anxiety, but what if it compromises your cognitive abilities (e.g. critical thinking, problem solving, planning, etc.)?  Agents such as benzodiazepines are linked to memory problems and generally impair functionality despite reducing anxiety.  Research has highlighted CBD’s ability to reduce anxiety without impairing cognitive function.

Based on reviews, smoking or vaporizing CBD vape oil seems to have less effects when compared to other methods of administering CBD, such as tinctures, capsules and sprays. On the flip side, others argue that smoking or vaporizing has less drawbacks than taking CBD orally, since ingesting CBD orally could result in inconsistent absorption and a delayed effect.


Forty million Americans suffer from anxiety. Anxiety is a state of worry that can be experienced in varying intensities. Mild anxiety can be characterized by that feeling of having butterflies in your stomach and is generally considered normal. However, anxiety can often be debilitating to a person impacting their social, professional, and personal lives. Anxiety disorder is an umbrella term, describing conditions where anxiety interferes with a person’s everyday life. Phobias, social anxiety, panic disorder and even obsessive-compulsive disorder are considered anxiety disorders. Common symptoms of anxiety include dizziness, panic, insomnia, tingling hands or feet, shortness of breath, nausea, and tense muscles. For many, anxiety is a driving force behind how they live their everyday lives and people are increasingly turning to CBD and other natural remedies to find relief.


And then I woke up on the concrete, a worried crowd gathered around me. “You had a seizure,” my friend said gently as I blinked my eyes, trying to process this new information.  I remember it was warm that night because I was wearing a sundress, and when I finally regained consciousness my first worry was that my dress flew up and everyone could see my underwear.

Safety: As of current, there’s zero evidence to suggest that cannabidiol is unsafe and/or intolerable. While certain individuals may experience adverse effects from its administration, these adverse effects are not common and may be a result of: poor sourcing, formatting, addition of other unwanted chemicals or cannabinoids, or contamination.  Most research indicates CBD is just as safe and well-tolerated as a placebo.
No medication seemed to provide a great deal of relief for Harper’s symptoms. But in 2013, three years after their trip to Boston, Penny and Dustin caught an installment of CNN’s medical marijuana documentary and began researching what they could obtain in Texas, where medical marijuana is illegal. Their internet searches soon led them to HempMedsPx and Real Scientific Hemp Oil. The company sent Penny a vial of hemp oil, which she administered to Harper that September.
Despite that, he’s not particularly in favor of legalizing cannabis for recreational use. He doesn’t think anyone should go to jail for possessing it, but he insists that marijuana is “not an innocuous substance”—especially for young people. He cites studies showing that the prolonged use of high-THC strains of marijuana can change the way the developing brain grows. He notes that in some people cannabis can provoke serious and debilitating anxiety attacks. And he points to studies that suggest cannabis may trigger the onset of schizophrenia among those who have a genetic predisposition to the disease.
Cannabidiol (CBD), a Cannabis sativa constituent, is a pharmacologically broad-spectrum drug that in recent years has drawn increasing interest as a treatment for a range of neuropsychiatric disorders. The purpose of the current review is to determine CBD’s potential as a treatment for anxiety-related disorders, by assessing evidence from preclinical, human experimental, clinical, and epidemiological studies. We found that existing preclinical evidence strongly supports CBD as a treatment for generalized anxiety disorder, panic disorder, social anxiety disorder, obsessive–compulsive disorder, and post-traumatic stress disorder when administered acutely; however, few studies have investigated chronic CBD dosing. Likewise, evidence from human studies supports an anxiolytic role of CBD, but is currently limited to acute dosing, also with few studies in clinical populations. Overall, current evidence indicates CBD has considerable potential as a treatment for multiple anxiety disorders, with need for further study of chronic and therapeutic effects in relevant clinical populations.
CBD is showing real promise as a compound that can contribute to protecting the brain, thanks to its anti-oxidant and anti-inflammatory abilities. Scientists are investigating its role in neurogenesis and its ability to help the brain heal from injury, and as a treatment for neurodegenerative disease. Research suggests that CBD may help to reduce brain damage from stroke or other neurological injury. And CBD is increasingly looked to as a possible therapy for several neurodegenerative diseases, including Parkinson’s, Alzheimer’s, and multiple sclerosis.
Given the current state of evidence, it is important to avoid assuming CBD is a sustainable long-term intervention for anxiety disorders.  As further research is conducted with larger-scale, longer-term, robustly designed trials – we will better understand the anxiolytic capacity of CBD.  Those with refractory cases of anxiety in search of an alternative pharmacological intervention may want to discuss the feasibility of “as-needed” CBD administration with a medical professional.
Cannabidiol has drawn everybody’s attention when parents have discovered that the cannabis plant can significantly reduce epileptic seizures in children. Since then, CBD has become outstandingly popular; It won’t be an exaggeration if we say that cannabidiol has now more of a spotlight than THC, its intoxicating counterpart. Now widely available through online vendors and at health stores near you, CBD is taking the world by storm.
Linda – you are right. Each oil helps with a different condition. Also the potency level will determine the effectiveness of the oil. And of course you have the state of your condition. You’re best bet would be to contact the company that you’re interested in purchasing from and ask them which oil will work best for you. They will probably ask you a whole range of questions. Try purekana, they are pretty responsive
The consequences of sleep deficiency include multiple adverse outcomes. You can expect deterioration in all aspects of your health and wellbeing. Lack of sleep and/or poor-quality sleep will age you prematurely, compromise your decision making, dramatically decrease your athletic performance, and increase the risk of injury. Alcohol or drug-induced sleep is not the healthy, restorative sleep the mind and body needs either.
In this article, we ranked the best CBD oils for sleep according to quality, the company’s customer support, the extraction process, and of course, personal use. All five CBD oils have been amazing for many individuals in terms of sleep, insomnia or related issues, and as we tend not to play favorites, we can’t recommend just one. Instead, we’ll go ahead and tell you that the two CBD oil companies that were voted by our team as the best of 2018 are:
If you’re like me, I think you’ll agree with me when I say that lack of sleep really interrupts your life. You can become cranky and irritable, snapping at friends and colleagues while your body is screaming for rest. Maybe you’ve gone down the laundry list of “fixes” — meditation, yoga, alcohol, exercise, an electronics detox before bed, you know the drill— but nothing seems to be working. It can be frustrating beyond measure.
Cannabidiol (CBD), a Cannabis sativa constituent, is a pharmacologically broad-spectrum drug that in recent years has drawn increasing interest as a treatment for a range of neuropsychiatric disorders. The purpose of the current review is to determine CBD’s potential as a treatment for anxiety-related disorders, by assessing evidence from preclinical, human experimental, clinical, and epidemiological studies. We found that existing preclinical evidence strongly supports CBD as a treatment for generalized anxiety disorder, panic disorder, social anxiety disorder, obsessive–compulsive disorder, and post-traumatic stress disorder when administered acutely; however, few studies have investigated chronic CBD dosing. Likewise, evidence from human studies supports an anxiolytic role of CBD, but is currently limited to acute dosing, also with few studies in clinical populations. Overall, current evidence indicates CBD has considerable potential as a treatment for multiple anxiety disorders, with need for further study of chronic and therapeutic effects in relevant clinical populations.
Based on the existing scientific literature, it is impossible to conclude whether CBD is therapeutically effective as a treatment for anxiety disorders – especially when administered chronically and/or over a long-term.  However, considerable evidence supports the efficacy of CBD when administered acutely for: social phobia, public speaking anxiety, and environmental stress.  Acute administration of CBD appears to improve subjective, physiological, and objective measures of anxiety in stressful situations.
Cannabis oils and CBD oils are not the same thing. So what is CBD oil? Cannabidiol (CBD) oil has a high concentration of cannabidiol, while cannabis oil contains both CBD and THC. CBD oil is created by extracting CBD from either the cannabis or hemp plant and then diluting it with a carrier oil like coconut or hemp seed oil. CBD does not produce a euphoric “high” or psychoactive effect because it doesn’t affect the same receptors as THC.

My MD has prescribed at least 20 different BP drugs for me, but I do not feel that any really worked; and some were so dangerous that I refused to used them more than one or 2 nights, and then would disgard them, especially after reading about the possible side effects. Never tried CBD oil, but my guru nutritionist has given me a bottle of 1200mg organic hemp oil from Veggimins and I have been hesitant to really try it.
Both Bonn-Miller and Ward stress that it's up to the consumer to be well-educated about the material they're purchasing and the research that's out there. "The companies that are creating [cannabis oils] are offering lots of claims about its use that are not necessarily substantiated by any research," Bonn-Miller said. So "I think there needs to be, from a consumer standpoint, a lot of vigilance," he added.

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Medical Disclaimer: Statements in any video or written content on this site have not been evaluated by the FDA. If you are pregnant, nursing, taking medications, or have a medical condition, consult your physician before using this product. Representations regarding the efficacy and safety of CBD oil have not been evaluated by the Food and Drug Administration. The FDA only evaluates foods and drugs, not supplements like these products. These products are not intended to diagnose, prevent, treat, or cure any disease. The material on this site is provided for informational purposes only and is not medical advice. Always consult your physician before beginning any supplement program.

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