Hi, I had ovarian cancer stage 2 and went to do chemotherapy for 16 times in 2014. It came back last year 2016 but I did not do chemotherapy or radiation therapy as suggested by the doctor. I am taking hormone therapy at the moment. I would like to use cannabis oil but which one and how much CBD and how much THC should I take for ovarian cancer? Can anyone give some idea?. Thank you very much.
I tested positive during an ER visit in a state that is unfriendly toward CBD oil. I was taking the highest strength product from a major brand, the one made by the brothers. I’m over 40 and weigh around 250 pounds, and I don’t use anything else that contains THC or CBD. I was shocked it showed up in the test and more shocked by how I was treated by the ER staff after the results of the test.
My mom is late stage dementia. We have tried coconut oil/black pepper/curcumin combo for years. Gives only tine bit of help, and is not something that reverses dementia. Maybe in someone who can score better than a 14 on the mme it could be of help. But cannabinoid is a different story. Cannabinoids produce better results in less time. Can't say yet that they will reverse anything though.
Funding. AZ, JH, FG, and JC are recipients of fellowship awards from Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq, Brazil – 1A). The present study was supported by a CNPq grant (CNPq/MS/SCTIE/DECIT N° 26/2014 – Pesquisas sobre Distúrbios Neuropsiquiátricos; 466805/2014-4) and STI-Pharm (Brentwood, United Kingdom) has kindly supplied CBD at no cost. IL and JS are recipients of CNPq Fellowships.
In 1937, the U.S. Treasury Department introduced the Marihuana Tax Act, which imposed a levy of $1 per ounce for medicinal use of cannabis and $100 per ounce for recreational use. This was opposed by physicians who were not required to pay a special tax for prescribing cannabis, use special order forms to obtain it and keep records detailing its professional use. The American Medical Association believed that evidence of cannabis’ harmful effects was limited and the act would prevent further research into its medicinal worth.
Back pain can be extremely debilitating, and it’s understandable if you want to steer clear of pharmaceutical painkillers in favor of something a little more natural. That’s what makes this Green Label Raw CBD Oil from Herbal Renewals so special. Available in three sizes, it’s a potent concentrate that gets to work in around fifteen minutes, and it can last for up to twelve hours, bringing real relief to back aches.
And then I woke up on the concrete, a worried crowd gathered around me. “You had a seizure,” my friend said gently as I blinked my eyes, trying to process this new information. I remember it was warm that night because I was wearing a sundress, and when I finally regained consciousness my first worry was that my dress flew up and everyone could see my underwear.
Research reveals that CBD can is an effective treatment option with a wide array of natural health properties. Studies are still ongoing about the other positive characteristics of CBD, but it has been proven that consumption of this compound is relatively safe. Just as important, CBD is also legal in all 50 states without a prescription. Cannabis oil, however, does not enjoy the same legal umbrella due to its THC content and psychoactive properties. Therefore, users who purchase or use THC or Cannabis oil in states where marijuana is illegal may be breaking the law.
All I can say is that evening, I had a great dinner (pizza!) and sat on the couch watching TV in a state of genuine contentment. I actually remember thinking to myself while watching an episode of The Office, “holy crap, that CBD must’ve really actually worked.” I experienced no side effects whatsoever, and I went to bed that night and had a genuinely good sleep.
With some of the dreadful reactions I have had to medications I mostly say no to drugs. The psychotropics turn me psycho. I read about addictions and have been through thus…I went off cold turkey with pain medication, antidepressants, anti psychotics, anti anxiety…I do not care to go through anything like that again. If I can get something stronger than an OTC I only want a low dose and do not want to go through what I did in 2010 again. This is where I am currently. Maybe my pain is not as severe as pain is for others. I do know what withdrawal is like and…I have had a good life all in all. I endeavor to be content and learn what I can. I do know what does not work for me.
During the study, 50 participants with PTSD coexisting with alcohol use disorder will be given either 400 milligrams of CBD daily, or a placebo. The goal is to see if the participants who take CBD end up drinking less and whether this leads to an improvement in PTSD symptoms. The participants will be given a pharmaceutical-grade CBD, which is more reliable in strength and purity than the supplements that are currently available for sale to the public.
However, I have always been extremely wary of using drugs to treat my condition – no matter how bad it is. I have seen therapists and medical doctors on several occasions for anxiety-related issues (including insomnia and panic attacks), and have been prescribed Xanax once, but I have never actually used a prescription medication to treat my condition. In fact, the one Xanax prescription that was prescribed for me, I never even got filled.
I assume this is also a side effect of the eased anxiety, but I seem to fall asleep within the 20- to 30-minute range rather than my normal 45 minutes to one hour (or longer). Not only do I seem to be skipping (or at least shortening) the whole tossing-and-turning phase of my sleep cycle, but I'm able to snap out of the overthinking mindset that often keeps me up at night. Of course, there's no telling whether a big life event would kindly disrupt this newfound bliss, but I'd like to think it's helped on day-to-day basis.
Epilepsy Society supports the Government in reviewing the regulatory framework for new drugs so that children with epilepsy have access to the excellent medical research and innovative treatments in this country, in the same way as disabled children in other leading North American and European countries. This could lead to clinicians being able to request a licence for a THC product where there is evidence that it would benefit the patient.
Hello and thanks for your comment. I’m sorry to hear you haven’t had any success with the CBD for helping you sleep. Most people find that CBD helps them get to sleep better if taken within 1 hour of going to bed. How much have you been taking? As long as you are comfortable with it, you may want to increase the dose a little bit to see if that has a better effect for sleep.
The relative representativeness of the small sample size and the use of a single dose of CBD can perhaps be regarded as a limitation of our study, as it does not allow the assessment of the effects of chronic treatment with CBD on sleep. In the study by Chagas et al. (2014b), for example, CBD was chronically administered for 6 weeks to patients with Parkinson’s disease and REM sleep behavior disorder. Since the effects of CBD are biphasic (Zuardi et al., 2017), the use of a single dose also limits the interpretation of the present findings. Moreover, monitoring changes in sleep using a conventional polysomnography presents some intrinsic limitations, as it is insufficient alone to detect drug-induced changes of the sleep EEG. For this purpose, a spectral analysis or a similar procedure is also needed. Conversely, the use of preclinical polysomnography to characterize drug-induced sleep disturbances has been increasingly recommended in the regulatory context (Authier et al., 2016). Finally, it is essential to evaluate the effects of CBD in a larger sample and in individuals diagnosed with sleep disorders in addition to healthy volunteers.
Hippocampal neurogenesis: One hypothesized mechanism by which pharmaceutical anxiolytics may decrease anxiety is via hippocampal neurogenesis – or growth of new neurons within the hippocampus. It appears as though cannabidiol administration induces hippocampal neurogenesis in animal models, and for this reason, similar outcomes may occur in humans. A rat study involving the chronic administration of 5-HT1A partial agonist (tandospirone) increases the biomarker of doublecortin – indicating emergence of new neurons in the hippocampus.
Runners pushing themselves daily might want to try more. Floyd’s of Leadville owner Bob Bell says that the company’s 50-milligram soft gels are its top seller. Talansky says his baseline is a 25-milligram gel, plus applying a strong topical cream three to five times a day if a specific body part is bothering him. He takes more on his hardest training days to speed recovery.
Support for legalization has steadily grown over the last several years. Today, medical marijuana is legal in 23 states and the District of Columbia. And even federal officials have begun to soften their stances. Last fall, outgoing Attorney General Eric Holder signaled his support for removing marijuana from the list of Schedule I narcotics. “I think it’s certainly a question we need to ask ourselves, whether or not marijuana is as serious of a drug as heroin,” Holder said. This summer, Chuck Rosenberg, the acting administrator of the U.S. Drug Enforcement Administration, acknowledged that marijuana is not as dangerous as other Schedule I drugs and announced his agents would not be prioritizing marijuana enforcement. Still, as long as marijuana remains illegal under federal law, the haphazard system in which it is studied, produced, and distributed will remain, and Americans will not be able to take full advantage of its medicinal properties.
From this study we can conclude that the acute effects of THC (e.g. increased anxiety) are unfavorable. Evidence suggests that CBD appears well-tolerated and safe, with no adverse physiological reactions compared to a placebo. However, since the physiological effects of CBD (600 mg) were of no statistically significant difference from the placebo, it is unclear if CBD elicits any therapeutic effect – even at a seemingly reasonable dose.
Cost: For high quality, unadulterated CBD – you’re going to pay a hefty price. Assuming you don’t want a product with pesticides, herbicides, fertilizers, and/or other chemical additives, you’ll likely end up paying a significant amount for just a few doses. Until scientists figure out a way to enhance CBD’s bioavailability, regular users of oral CBD may feel as if the supplement is too costly. Fortunately, there are other ways to administer cannabidiol such as vaporizing the oil – which will likely save consumers money.
I’ve been on anti-depressants for 11 years since having a stroke and having to stop taking estrogen. I started on Zoloft, then celexa, then Effexor. I’ve been having bad blurry vision for a few years that has my eye dr stumped. Finally my primary doctor thought it could be the Effexor since that is one of the side effects. So we decided that I would wean off the Effexor and try Wellbutrin instead. I lowered the amount of Effexor over 3 weeks till I wasn’t taking it any longer but started the Wellbutrin the last week of taking Effexor. After 3 days of no Effexor the withdrawals seemed to hit me. Headaches, nausea, extremely emotional, and bad dizziness. I had an important event to go to on day 3 of no Effexor so I took a low dose (37.5 mg) hoping to get me through the night. I felt decent for a couple days then boom, the withdrawal symptoms came on fully again. So I decided I would just try to go off both the Effexor and Wellbutrin because I didn’t want to go through this again and really wanted to see if I could handle life without them. Well it’s been a week without any Effexor but the dizziness and emotional outrages are still going on. I’ve been using Bonine (motion sickness) which does seem to help a little. My daughter mentioned the CBD oil which I was totally against at first but after doing a lot of research I am now quite interested in it.
Furthermore, THC and CBD oils also differ in the nature and effect of their Cannabinoid content. Cannabinoids typically bind to receptor sites located in the brain, called CB-1, and various parts of the human body called CB-2. But different cannabinoids produce different effects depending on which type of receptor they bind to. THC mostly binds to receptors in the brain, but CBD unlocks the receptors scattered throughout the body, making it far more useful for healing properties.
Earlier preclinical studies have suggested that the therapeutic effects of CBD might depend on the presence of specific clinical conditions. As an example, Campos et al. (2013) showed that the chronic use of CBD for 2 weeks, while not directly increasing hippocampal neurogenesis, prevented its decrease by unpredictable chronic stress. Thus, the absence of changes in the sleep of healthy volunteers treated with CDB in our study should not be considered as a final indication that CBD could not have positive effects in patients with sleep disorders.
When all is said and done, CBD oil is of course relatively new compared to traditional medicine, and therefore a patient with sleep trouble should always discuss CBD with a qualified healthcare professional before using. Also, as we have mentioned it’s important to understand that CBD has not been a clinically-verified form of treatment for insomnia.
Hippocampal neurogenesis: The hippocampus is a major brain area, and plays a critical role in a variety of brain functions. It’s most famous for its role in memory formation and cognition. Brain scans of patients suffering from depression or anxiety often show a smaller hippocampus, and successful treatment of depression is associated with the birth of new neurons (neurogenesis) in the hippocampus.
One of the strongest nutraceutical CBD oils is called Charlotte’s Web, with a 50mg dose. Charlotte’s Web is produced in Colorado by the Stanley Brothers, and named after Charlotte Figi, a girl who became famous in the US after her frequent seizures, brought on by the rare Dravet syndrome, were greatly reduced when she started taking CBD oil aged five. The company makes THC products too and is extremely successful, having just offered shares on the Canadian securities exchange, raising about $100m.
Anyone who wants a safe, natural health supplement can use CBD. Some people take it just to boost their body’s systems and balance their general health. Others take it to treat specific ailments, such as anxiety, pain, inflammation, and even epilepsy and some nerve and muscle afflictions. While the FDA hasn’t’ approved CBD oil and it shouldn’t be considered a medicine, an increasing number of people all over the world have discovered the healing properties of high CBD liquid. Everyone wonders what the future may hold. We will soon find out.
Great Article on CBD – Did you learn anything about how the efficacy of the CBC is affected by the source species? e.g. Cannabis vs Hemp. Also, Sativa vs. Indica. All of the referenced studies just state CBC, do you know what is the typical source of CBD used in these type of studies? CBC oil from Hemp is readily and cheaply available on the internet from many companies, however I have read that the efficacy of Hemp derived CBD is less than from Cannabis. Any thoughts? Thanks!
CBD products that don't contain THC fall outside the scope of the U.S. Drug Enforcement Agency's (DEA) Controlled Substances Act, which means CBD products are legal to sell and consume as long as they don't have THC. That's likely one of the reasons why CBD products, including CBD oil, are becoming more socially acceptable and increasingly popular. In 2016, Forbes reported that CBD products are expected to be a $2.2 billion industry by 2020.
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